Title:
タンパク質ナノ粒子分散系
Document Type and Number:
Japanese Patent JP2014514275
Kind Code:
A
Abstract:
Provided herein, inter alia, are protein dispersions comprising dense protein nanoclusters and methods of making the. Upon dilution, the clusters may reversibly dissociate into native protein molecules with high biological activity. The viscosities of the nanocluster dispersions may be sufficiently low to allow small-volume subcutaneous injections.
Inventors:
Johnston, Keith, Pea.
Maynard, Jennifer, A.
Mirror, Andrea
Brian Wilson
Trusket, Thomas, M.
Dynein, Irene
Bow wanker, ameyah
Maynard, Jennifer, A.
Mirror, Andrea
Brian Wilson
Trusket, Thomas, M.
Dynein, Irene
Bow wanker, ameyah
Application Number:
JP2013557933A
Publication Date:
June 19, 2014
Filing Date:
March 09, 2012
Export Citation:
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
A61K38/00; A61K9/10; A61K47/10; A61K47/14; A61K47/18; A61K47/22; A61K47/26; A61K47/34; A61K47/36; A61K47/42; A61K47/44; A61P35/00; B82Y5/00; B82Y30/00; B82Y40/00
Domestic Patent References:
| JP2007517023A | 2007-06-28 | |||
| JPH0899897A | 1996-04-16 |
Foreign References:
| WO2010056657A2 | 2010-05-20 | |||
| WO2010009146A1 | 2010-01-21 | |||
| WO2010139442A1 | 2010-12-09 |
Attorney, Agent or Firm:
Seiji Ohno
Keiko Kanemoto
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito
Umeda Shinsuke
Keiko Kanemoto
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito
Umeda Shinsuke