Title:
タンパク質分離装置
Document Type and Number:
Japanese Patent JP2008504006
Kind Code:
A
Abstract:
The invention provides a protein separation device comprising a chaperone protein immobilized on a substrate. In one embodiment, the chaperone protein is an Hsp60 chaperone, preferably a group one chaperone, preferably GroEL. The invention also provides a method for isolating a protein from a biological sample using a protein separation device of the invention.
Inventors:
Tsai, Hen Han
Raeung, Hong-Chiu Eastwood
Raeung, Hong-Chiu Eastwood
Application Number:
JP2006545304A
Publication Date:
February 14, 2008
Filing Date:
December 17, 2004
Export Citation:
Assignee:
AGENCY FOR SCIENCE,TECHNOLOGY AND RESEARCH
International Classes:
C12N15/09; B01J20/24; C07K1/22; C07K14/195; C07K14/245; C07K14/47; C12M1/00; G01N33/68
Domestic Patent References:
| JPH0748398A | 1995-02-21 | |||
| JPH0748398A | 1995-02-21 |
Foreign References:
| WO2003061570A2 | 2003-07-31 | |||
| WO2003061570A2 | 2003-07-31 |
Other References:
JPN6010040543, ＢＡＬＬ， Ｈ．Ｌ． ｅｔ ａｌ．, "”Ａｐｐｌｉｃａｔｉｏｎ ｏｆ ｒｅｖｅｒｓｉｂｌｅ ｂｉｏｔｉｎｙｌａｔｅｄ ｌａｂｅｌ ｆｏｒ ｄｉｒｅｃｔｅｄ ｉｍｍｏｂｉｌｉｚａｔｉｏｎ ｏｆ ｓｙｎｔｈｅｔｉｃ ｐｅｐｔｉｄｅｓ ａｎｄ", Ｊ． ＰＥＰＴ． ＳＣＩ．, 199707, Ｖｏｌ．３， Ｎｏ．４, Ｐ．２５２−２６０
JPN6010040544, ＰＲＥＳＴＯＮ， Ｎ．Ｓ． ｅｔ ａｌ．, "”Ｔｈｅ ｐｒｏｄｕｃｔｉｏｎ ａｎｄ ｃｈａｒａｃｔｅｒｉｓａｔｉｏｎ ｏｆ ａｎ ｉｍｍｏｂｉｌｉｓｅｄ ｃｈａｐｅｒｏｎｉｎ ｓｙｓｔｅｍ．”", ＢＩＯＣＨＩＭ． ＢＩＯＰＨＹＳ． ＡＣＴＡ, 19990104, Ｖｏｌ．１４２６， Ｎｏ．１, Ｐ．９９−１０９
JPN6010040545, ＤＯＮＧ， Ｘ．Ｙ． ｅｔ ａｌ．, "”Ｌｙｓｏｚｙｍｅ ｒｅｆｏｌｄｉｎｇ ｗｉｔｈ ｉｍｍｏｂｉｌｉｚｅｄ ＧｒｏＥＬ ｃｏｌｕｍｎ ｃｈｒｏｍａｔｏｇｒａｐｈｙ．”", Ｊ． ＣＨＲＯＭＡＴＯＧＲ． Ａ, 20000512, Ｖｏｌ．８７８， Ｎｏ．２, Ｐ．１９７−２０４
JPN6010040547, ＥＶＥＲＳ， Ｍ．Ｅ． ｅｔ ａｌ．, "”Ａｆｆｉｎｉｔｙ ｐｕｒｉｆｉｃａｔｉｏｎ ｏｆ ｍｏｌｅｃｕｌａｒ ｃｈａｐｅｒｏｎｅｓ ｏｆ ｔｈｅ ｙｅａｓｔ Ｈａｎｓｅｎｕｌａ ｐｏｌｙｍｏｒｐｈａ ｕｓｉｎｇ ｉｍｍｏｂｉｌｉｚｅｄ ｄ", ＦＥＢＳ ＬＥＴＴ．, 19930419, Ｖｏｌ．３２１， Ｎｏ．１, Ｐ．３２−３６
JPN6010040548, ＮＡＭ， Ｓ．Ｈ． ｅｔ ａｌ．, "”Ａｆｆｉｎｉｔｙ ｐｕｒｉｆｉｃａｔｉｏｎ ａｎｄ ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ ｏｆ ｔｈｅ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ ｍｏｌｅｃｕｌａｒ ｃｈａｐｅｒｏｎｅｓ．”", ＰＲＯＴＥＩＮ ＥＸＰＲ． ＰＵＲＩＦ．, 200203, Ｖｏｌ．２４， Ｎｏ．２, Ｐ．２８２−２９１
JPN6010040550, ＧＡＯ， Ｙ．Ｇ． ｅｔ ａｌ．, "”Ｏｎ−ｃｏｌｕｍｎ ｒｅｆｏｌｄｉｎｇ ｏｆ ｒｅｃｏｍｂｉｎａｎｔ ｈｕｍａｎ ｉｎｔｅｒｆｅｒｏｎ−ｇａｍｍａ ｗｉｔｈ ａｎ ｉｍｍｏｂｉｌｉｚｅｄ ｃｈａｐｅｒｏｎｅ ｆｒａｇｍｅｎｔ．”", ＢＩＯＴＥＣＨＮＯＬ． ＰＲＯＧ．, 200305, Ｖｏｌ．１９， Ｎｏ．３, Ｐ．９１５−９２０
JPN6010040552, ＶＩＩＴＡＮＥＮ， Ｐ．Ｖ． ｅｔ ａｌ．, "”Ｐｕｒｉｆｉｅｄ ｃｈａｐｅｒｏｎｉｎ ６０ （ｇｒｏＥＬ） ｉｎｔｅｒａｃｔｓ ｗｉｔｈ ｔｈｅ ｎｏｎｎａｔｉｖｅ ｓｔａｔｅｓ ｏｆ ａ ｍｕｌｔｉｔｕｄｅ ｏｆ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏ", ＰＲＯＴＥＩＮ ＳＣＩ．, 199203, Ｖｏｌ．１， Ｎｏ．３, Ｐ．３６３−３６９
JPN6010040554, ＰＨＡＤＴＡＲＥ， Ｓ． ｅｔ ａｌ．, "”Ｒｅｆｏｌｄｉｎｇ ａｎｄ ｒｅｌｅａｓｅ ｏｆ ｔｕｂｕｌｉｎｓ ｂｙ ａ ｆｕｎｃｔｉｏｎａｌ ｉｍｍｏｂｉｌｉｚｅｄ ｇｒｏＥＬ ｃｏｌｕｍｎ．”", ＢＩＯＣＨＩＭ． ＢＩＯＰＨＹＳ． ＡＣＴＡ, 19940921, Ｖｏｌ．１２０８， Ｎｏ．１, Ｐ．１８９−１９２
JPN6010040555, ＮＩＥＢＡ， Ｌ． ｅｔ ａｌ．, "”ＢＩＡＣＯＲＥ ａｎａｌｙｓｉｓ ｏｆ ｈｉｓｔｉｄｉｎｅ−ｔａｇｇｅｄ ｐｒｏｔｅｉｎｓ ｕｓｉｎｇ ａ ｃｈｅｌａｔｉｎｇ ＮＴＡ ｓｅｎｓｏｒ ｃｈｉｐ．”", ＡＮＡＬ． ＢＩＯＣＨＥＭ．, 19971015, Ｖｏｌ．２５２， Ｎｏ．２, Ｐ．２１７−２２８
JPN6010040544, ＰＲＥＳＴＯＮ， Ｎ．Ｓ． ｅｔ ａｌ．, "”Ｔｈｅ ｐｒｏｄｕｃｔｉｏｎ ａｎｄ ｃｈａｒａｃｔｅｒｉｓａｔｉｏｎ ｏｆ ａｎ ｉｍｍｏｂｉｌｉｓｅｄ ｃｈａｐｅｒｏｎｉｎ ｓｙｓｔｅｍ．”", ＢＩＯＣＨＩＭ． ＢＩＯＰＨＹＳ． ＡＣＴＡ, 19990104, Ｖｏｌ．１４２６， Ｎｏ．１, Ｐ．９９−１０９
JPN6010040545, ＤＯＮＧ， Ｘ．Ｙ． ｅｔ ａｌ．, "”Ｌｙｓｏｚｙｍｅ ｒｅｆｏｌｄｉｎｇ ｗｉｔｈ ｉｍｍｏｂｉｌｉｚｅｄ ＧｒｏＥＬ ｃｏｌｕｍｎ ｃｈｒｏｍａｔｏｇｒａｐｈｙ．”", Ｊ． ＣＨＲＯＭＡＴＯＧＲ． Ａ, 20000512, Ｖｏｌ．８７８， Ｎｏ．２, Ｐ．１９７−２０４
JPN6010040547, ＥＶＥＲＳ， Ｍ．Ｅ． ｅｔ ａｌ．, "”Ａｆｆｉｎｉｔｙ ｐｕｒｉｆｉｃａｔｉｏｎ ｏｆ ｍｏｌｅｃｕｌａｒ ｃｈａｐｅｒｏｎｅｓ ｏｆ ｔｈｅ ｙｅａｓｔ Ｈａｎｓｅｎｕｌａ ｐｏｌｙｍｏｒｐｈａ ｕｓｉｎｇ ｉｍｍｏｂｉｌｉｚｅｄ ｄ", ＦＥＢＳ ＬＥＴＴ．, 19930419, Ｖｏｌ．３２１， Ｎｏ．１, Ｐ．３２−３６
JPN6010040548, ＮＡＭ， Ｓ．Ｈ． ｅｔ ａｌ．, "”Ａｆｆｉｎｉｔｙ ｐｕｒｉｆｉｃａｔｉｏｎ ａｎｄ ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ ｏｆ ｔｈｅ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ ｍｏｌｅｃｕｌａｒ ｃｈａｐｅｒｏｎｅｓ．”", ＰＲＯＴＥＩＮ ＥＸＰＲ． ＰＵＲＩＦ．, 200203, Ｖｏｌ．２４， Ｎｏ．２, Ｐ．２８２−２９１
JPN6010040550, ＧＡＯ， Ｙ．Ｇ． ｅｔ ａｌ．, "”Ｏｎ−ｃｏｌｕｍｎ ｒｅｆｏｌｄｉｎｇ ｏｆ ｒｅｃｏｍｂｉｎａｎｔ ｈｕｍａｎ ｉｎｔｅｒｆｅｒｏｎ−ｇａｍｍａ ｗｉｔｈ ａｎ ｉｍｍｏｂｉｌｉｚｅｄ ｃｈａｐｅｒｏｎｅ ｆｒａｇｍｅｎｔ．”", ＢＩＯＴＥＣＨＮＯＬ． ＰＲＯＧ．, 200305, Ｖｏｌ．１９， Ｎｏ．３, Ｐ．９１５−９２０
JPN6010040552, ＶＩＩＴＡＮＥＮ， Ｐ．Ｖ． ｅｔ ａｌ．, "”Ｐｕｒｉｆｉｅｄ ｃｈａｐｅｒｏｎｉｎ ６０ （ｇｒｏＥＬ） ｉｎｔｅｒａｃｔｓ ｗｉｔｈ ｔｈｅ ｎｏｎｎａｔｉｖｅ ｓｔａｔｅｓ ｏｆ ａ ｍｕｌｔｉｔｕｄｅ ｏｆ Ｅｓｃｈｅｒｉｃｈｉａ ｃｏ", ＰＲＯＴＥＩＮ ＳＣＩ．, 199203, Ｖｏｌ．１， Ｎｏ．３, Ｐ．３６３−３６９
JPN6010040554, ＰＨＡＤＴＡＲＥ， Ｓ． ｅｔ ａｌ．, "”Ｒｅｆｏｌｄｉｎｇ ａｎｄ ｒｅｌｅａｓｅ ｏｆ ｔｕｂｕｌｉｎｓ ｂｙ ａ ｆｕｎｃｔｉｏｎａｌ ｉｍｍｏｂｉｌｉｚｅｄ ｇｒｏＥＬ ｃｏｌｕｍｎ．”", ＢＩＯＣＨＩＭ． ＢＩＯＰＨＹＳ． ＡＣＴＡ, 19940921, Ｖｏｌ．１２０８， Ｎｏ．１, Ｐ．１８９−１９２
JPN6010040555, ＮＩＥＢＡ， Ｌ． ｅｔ ａｌ．, "”ＢＩＡＣＯＲＥ ａｎａｌｙｓｉｓ ｏｆ ｈｉｓｔｉｄｉｎｅ−ｔａｇｇｅｄ ｐｒｏｔｅｉｎｓ ｕｓｉｎｇ ａ ｃｈｅｌａｔｉｎｇ ＮＴＡ ｓｅｎｓｏｒ ｃｈｉｐ．”", ＡＮＡＬ． ＢＩＯＣＨＥＭ．, 19971015, Ｖｏｌ．２５２， Ｎｏ．２, Ｐ．２１７−２２８
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Ryo Hashimoto
Tetsuya Kazama