PROTEIN STABILIZATION IN SOLUTION - NOVO NORDISK HEALTHCARE AG

Title:

PROTEIN STABILIZATION IN SOLUTION

Document Type and Number:

Japanese Patent JP2012229230

Kind Code:

A

Abstract:

To provide an inner wall material in a container for the containment and storage of a pharmaceutical formulation of a protein, in particular a vitamin K-dependent coagulation protein, such as Factor Vlla.

The material is selected from the group consisting of: silica-coated glass, silicone-coated glass, polymers of non-cyclic olefins, cycloolefin polymers and cycloolefin/linear olefin copolymers.

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Inventors:

JENSEN MICHAEL BECH
HANSEN BIRTHE LYKKEGAARD
KORNFELT TROELS
JAKOBSEN KIRSTEN KRAMER

Application Number:

JP2012139978A

Publication Date:

November 22, 2012

Filing Date:

June 21, 2012

Export Citation:

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Assignee:

NOVO NORDISK HEALTHCARE AG

International Classes:

A61K9/08; A61J3/07; A61K9/19; A61K38/00; A61K38/43; A61K38/46; A61K38/48; A61K47/02; A61P7/04

Domestic Patent References:

JPWO0117542A1
JPWO0015241A1
JP2001500867A	2001-01-23
JPH11335295A	1999-12-07
JP2003508500A	2003-03-04
JP2003508766A	2003-03-04

Other References:

JPN6014000374; Ｋｅｔｔｅｎｂｏｒｇ，　Ｈ．　Ｋ．　ｅｔ　ａｌ: 'Ｍｏｄｉｆｉｃａｔｉｏｎｓ　ｉｎ　ｔｈｅ　ｂｅｈａｖｉｏｒ　ｏｆ　ｃｏａｇｕｌａｔｉｏｎ　ｆａｃｔｏｒｓ　ｄｕｒｉｎｇ　ｓｔｏｒａｇｅ　ｏｆ　ｂｌｏｏｄ　ａｎｄ　ｉｔｓ　ｉｍｐｏｒｔａｎｃｅ　ｆｏｒ' Ｒｅｖ．　ｂｅｌｇｅ　ｐａｔｈｏｌ．　ｅｔ　ｍｅｄ．　ｅｘｐｔｌ．Ｖｏｌ．２４，Ｎｏ２．, 1955, ｐ１３６-１４０

Attorney, Agent or Firm:

Kurata Masatoshi
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Nobuhisa Nogawa
Kocho Chojiro
Naoki Kono
Katsu Sunagawa
Tatsushi Sato
Takashi Okada
Mihoko Horiuchi
Takenori Masanori

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