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Title:
Proteinkinase C inhibitor and its use
Document Type and Number:
Japanese Patent JP6113828
Kind Code:
B2
Abstract:
This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Inventors:
Thing, Razinder
Duckton, matthew
Chang, Jin
Alvarez, Salvador
Zo, kin
Holland, Sascha
Yen, Rose
Korli, Lao
Heck Road, Tiro
Chen, Yang
Masuda, Esteban
Li, Hui
Payang, Donald G.
Kerry, ryan
Application Number:
JP2015504725A
Publication Date:
April 12, 2017
Filing Date:
April 04, 2013
Export Citation:
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Assignee:
Rigel Pharmaceuticals, Inc.
International Classes:
C07D471/04; A61K31/506; A61K31/5377; A61K31/538; A61K31/5383; A61K31/5386; A61K31/553; A61P1/00; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P5/14; A61P7/08; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P17/08; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D519/00
Domestic Patent References:
JP2010518069A
JP2010533733A
Foreign References:
WO2011068898A1
Attorney, Agent or Firm:
Naoto Uchida