To suppress the pressure distribution and pressure fluctuation in the circulating passage of a pseudo moving bed type chromatographic separating device to suppress the concentration fluctuation of a circulating solution and to provide a desired separating performance.
This device has a circulating passage having separation columns endlessly connected thereto, so that a binary system raw material solution and an eluent are injected from tanks 12, 14, and separated components A and C are extracted to tanks 16, 18. As each of first and second circulating pumps 52, 56 for circulating the solution, a raw material solution injection pump 54 and an eluent injection pump 58, a 1-cylinder type plunger pump is used. The plungers of the first circulating pump 52 and the second circulating pump 56, and the plungers of the raw material solution injection pump 56 and the eluent injection pump 58 are set so as to have mutually reverse phases, respectively, and all the pumps are synchronously driven, whereby the pressure distribution and pressure fluctuation within the system are suppressed to prevent the fluctuation of the concentration distribution.
MATSUDA FUMIHIKO
MASUDA TAKAYUKI
SATO KOHEI
YASUDA MANABU
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