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Title:
PTERIDINONE COMPOUNDS AND USES THEREOF
Document Type and Number:
Japanese Patent JP2023116712
Kind Code:
A
Abstract:
To provide a method of treating disorders.SOLUTION: There is provided a compound of formula (I) or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferate disorders (e.g., cancer). It has now been found that compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful for treating proliferative disorders (e.g., cancer). In one aspect, the present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof. Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful for treating a variety of proliferative disorders (e.g., cancer).SELECTED DRAWING: Figure 1

Inventors:
LAUFFER DAVID J
GUY BEMIS
MICHAEL BOYD
DAVID DEININGER
DENG HONGBO
WARREN DORSCH
GU WENXIN
RUSSELL R HOOVER
MAC ARTHUR JOHNSON JR
MARK WILLEM LEDEBOER
LEDFORD BRIAN
MALTAIS FRANCOIS
MARINA PENNEY
DARIN TAKEMOTO
NATHAN D WAAL
WANG TIANSHENG
LI PAN
Application Number:
JP2023098522A
Publication Date:
August 22, 2023
Filing Date:
June 15, 2023
Export Citation:
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Assignee:
VERTEX PHARMA
International Classes:
C07D471/04; A61K31/4985; A61K31/519; A61P35/00; A61P43/00; C07D475/00
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita