Title:
PURIFICATION OF ESTRAMUSTINE PHOSPHATE OR ITS SALT
Document Type and Number:
Japanese Patent JP2554005
Kind Code:
B2
Abstract:
PURPOSE: To extremely easily obtain estramustine phosphate having high purity with a simple operation.
CONSTITUTION: Crude estramustine phosphate can be purified by dissolving the crude substance in a fatty acid ester, adding methanol (or ethanol) and water to the solution under acidic condition and collecting the precipitate.
Inventors:
OOWAKI KEIJI
NOROSE SATORU
SHINNO HIDEKI
NOROSE SATORU
SHINNO HIDEKI
Application Number:
JP5128893A
Publication Date:
November 13, 1996
Filing Date:
February 18, 1993
Export Citation:
Assignee:
PERMACHEM ASIA LTD
International Classes:
A61K31/565; A61P35/00; C07J1/00; C07J41/00; C07J51/00; (IPC1-7): C07J1/00; C07J51/00
Attorney, Agent or Firm:
Junichi Takahashi