Title:
癌治療用のＣＤ７３阻害剤としてのプリン誘導体
Document Type and Number:
Japanese Patent JP6657182
Kind Code:
B2
Abstract:
Provided are novel purine nucleoside/nucleotide analogues compounds, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are inhibitors of CD73 and are useful in the treatment of cancer.
Inventors:
Salvation Kakatian
David A. Claremon
Zia Lanti
Angel Morales-Ramos
Thresh Be Sin
Shankar Benkatraman
Shui Jenron
Yajun Jen
David A. Claremon
Zia Lanti
Angel Morales-Ramos
Thresh Be Sin
Shankar Benkatraman
Shui Jenron
Yajun Jen
Application Number:
JP2017507914A
Publication Date:
March 04, 2020
Filing Date:
April 23, 2015
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07H19/10; A61K31/675; A61P35/00; A61P43/00; C07H19/167; C07H19/20
Foreign References:
| WO2007135195A1 | ||||
| WO2003074083A1 |
Other References:
Journal of Organic Chemistry,2011年,Vol.76,pp.105-126
Tetrahedron,2012年,Vol.68,pp.1894-1909
Origins of Life and Evolution of Biospheres,2006年,Vol.36,pp.39-63
Glycoconjugate Journal,2006年,Vol.23,pp.371-375
Tetrahedron,2012年,Vol.68,pp.1894-1909
Origins of Life and Evolution of Biospheres,2006年,Vol.36,pp.39-63
Glycoconjugate Journal,2006年,Vol.23,pp.371-375
Attorney, Agent or Firm:
Shinichiro Tanaka
Disciple Maru Ken
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Disciple Maru Ken
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori