Title:
PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF
Document Type and Number:
Japanese Patent JP2021038245
Kind Code:
A
Abstract:
To provide pyrazole compounds, and pharmaceutically acceptable compositions thereof.SOLUTION: Disclosed are pyrazole compounds, and pharmaceutically acceptable compositions thereof. This compound and composition thereof can be used as positive allosteric modulators of follicle stimulating hormone receptor (FSHR). Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful for treating a variety of diseases, disorders or conditions, associated with abnormal cellular responses triggered by follicle stimulating hormone events. Such diseases, disorders, or conditions include those described herein.SELECTED DRAWING: None
Inventors:
HENRY YU
QI CHANGHE
PAUL TEMPEST
SELVARAJ G NATARAJA
STEPHEN S PALMER
QI CHANGHE
PAUL TEMPEST
SELVARAJ G NATARAJA
STEPHEN S PALMER
Application Number:
JP2020191715A
Publication Date:
March 11, 2021
Filing Date:
November 18, 2020
Export Citation:
Assignee:
ARES TRADING SA
International Classes:
C07D491/052; A61K31/4162; A61K31/4192; A61K31/4196; A61K31/422; A61K31/4439; A61K31/444; A61K31/454; A61K31/4545; A61K31/455; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/541; A61P5/06; A61P15/08; A61P43/00
Domestic Patent References:
| JP6557331B2 | 2019-08-07 | |||
| JP2013510825A | 2013-03-28 | |||
| JP2005510466A | 2005-04-21 | |||
| JPH03505204A | 1991-11-14 |
Foreign References:
| WO2014209980A1 | 2014-12-31 | |||
| WO2008035356A2 | 2008-03-27 |
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Hidena Tsuda
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Hidena Tsuda