Title:
CK2阻害剤としてのピラゾロピリミジンおよび関連複素環化合物
Document Type and Number:
Japanese Patent JP5802676
Kind Code:
B2
Abstract:
The invention provides compounds that inhibit protein kinase CK2 activity (CK2 activity), and compositions containing such compounds. These compounds and compositions are useful for treating proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, and certain immunological disorders, and have the following general formula:
Inventors:
Hadach mustafa
Tran Joe A.
Pierre Fabrice
Regan Colin F.
Raffaele Nicholas Bee.
Labra Sachitra
Rickman David M.
Tran Joe A.
Pierre Fabrice
Regan Colin F.
Raffaele Nicholas Bee.
Labra Sachitra
Rickman David M.
Application Number:
JP2012542060A
Publication Date:
October 28, 2015
Filing Date:
November 15, 2010
Export Citation:
Assignee:
Senwa Biosciences Inc.
International Classes:
A61K31/4985; C07D487/04; A61K31/519; A61K31/53; A61K31/5377; A61K31/551; A61K31/553; A61K45/00; A61P9/14; A61P25/28; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D519/00
Domestic Patent References:
JP2006519226A | ||||
JP2006502184A | ||||
JP2005538188A | ||||
JP2008511589A | ||||
JP2007523953A | ||||
JP2005530739A | ||||
JP2009544723A | ||||
JP2006500327A | ||||
JP2005513026A |
Foreign References:
WO2010135581A1 | ||||
WO2004028535A1 | ||||
WO2009100375A1 | ||||
WO2008046982A1 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto