PYRIDINE DERIVATIVE AS INHIBITOR OF P38

Title:

PYRIDINE DERIVATIVE AS INHIBITOR OF P38

Document Type and Number:

Japanese Patent JP2012149085

Kind Code:

A

Abstract:

To provide pyridine derivatives as inhibitors of P38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli.

The invention provides pharmaceutical compositions comprising a compound represented by the following formula 10 as the inhibitors.

Inventors:

COCHRAN JOHN
GALULLO VINCENT
BEMIS GUY

Application Number:

JP2012077626A

Publication Date:

August 09, 2012

Filing Date:

March 29, 2012

Export Citation:

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Assignee:

VERTEX PHARMA

International Classes:

C07D213/74; A61K31/4412; A61K31/4418; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P7/00; A61P7/02; A61P7/04; A61P7/06; A61P7/10; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P31/22; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C07D213/75; C07D401/12; C07F9/58

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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