Title:
PYRIDINE AND PYRIMIDINE DERIVATIVE HAVING TTK-INHIBITING ACTION
Document Type and Number:
Japanese Patent JP2012197231
Kind Code:
A
Abstract:
To provide an effective inhibitor of TTK protein kinase, and to provide an effective medicine.
There is provided a pyridine derivative or pyrimidine derivative represented by formula (I). (Wherein, X is =C(R4)- or =N-; A is a substituted or non-substituted aromatic hydrocarbon ring, substituted or non-substituted aromatic heterocycle (wherein, excluding substituted or non-substituted pyrazole or condensed pyrazole), substituted or non-substituted non-aromatic hydrocarbon ring or substituted or non-substituted non-aromatic heterocycle). The compound inhibits the action of TTK protein kinase, and is especially useful for preparing medicines for treating related diseases.
Inventors:
KUSAKABE KENICHI
YAMAGUCHI NAOKO
MITSUOKA YASUNORI
YAMAGUCHI NAOKO
MITSUOKA YASUNORI
Application Number:
JP2010121046A
Publication Date:
October 18, 2012
Filing Date:
May 26, 2010
Export Citation:
Assignee:
ONCOTHERAPY SCIENCE LTD
International Classes:
C07D213/76; A61K31/437; A61K31/44; A61K31/4439; A61K31/444; A61K31/455; A61K31/496; A61K31/506; A61K31/5377; A61P43/00; C07D213/82; C07D213/85; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D413/12; C07D413/14; C07D417/12; C07D471/04
Attorney, Agent or Firm:
井上 隆一
佐藤 利光
刑部 俊
大関 雅人
小林 智彦
山口 裕孝
川本 和弥
新見 浩一
春名 雅夫
清水 初志
渡邉 伸一
佐藤 利光
刑部 俊
大関 雅人
小林 智彦
山口 裕孝
川本 和弥
新見 浩一
春名 雅夫
清水 初志
渡邉 伸一
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