癌疾患の処置のためのエンドリボヌクレアーゼのイノシトール要求酵素Ｉ（ＩＲＥＩアルファ）の阻害剤としてのピリド－ピリミジノン化合物及びプテリジノン化合物

Title:

Document Type and Number:

Japanese Patent JP2022517189

Kind Code:

A

Abstract:

ピリド－ピリミジノン及びプテリジノン化合物、又はその立体異性体、互変異性体、若しくは薬学的に許容可能な塩、並びに置換基及び構造的特徴が本明細書に記載される。本明細書に記載の化合物を含む医薬組成物及び医薬、並びに単独で及び他の治療剤と組み合わせて癌を処置する方法も記載される。

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Inventors:

Brown, Marie-Gabriel
Castanade, Joe Jet
Gibbons, Paul
Rudolph, Joachim
Vernier, William
Beverage, Ramsey
Woo, Yao
Wu, Guoshon

Application Number:

JP2021539020A

Publication Date:

March 07, 2022

Filing Date:

January 02, 2020

Export Citation:

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Assignee:

Genentech, Incorporated

International Classes:

C07D471/04; A61K31/454; A61K31/519; A61K31/5377; A61K31/573; A61K31/69; A61K38/05; A61K38/07; A61K39/395; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07D475/00; C07D519/00

Attorney, Agent or Firm:

Yamato Kento
Sei Morimoto
Nobuhiko Akiyama

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