Title:
ピロリジン誘導体、その医薬組成物及び使用
Document Type and Number:
Japanese Patent JP6378752
Kind Code:
B2
Abstract:
Pyrrolidine derivatives which are inhibitors of acetyl-CoA carboxylase(s) and their use in the treatment of obesity and type-2 diabetes. An exemplary compound is 2-(4-(1-[5-Chloro-6-(2-hydroxy-2-methyl-propoxy)-pyrimidin-4-yl]-(R)-pyrrolidin-3-yloxy)-phenyl)-N-cyclopropyl-propionamide.
Inventors:
Heine Niclas
Fleck Martin
Nose Bernd
Roth Gerald Jürgen
Fleck Martin
Nose Bernd
Roth Gerald Jürgen
Application Number:
JP2016513304A
Publication Date:
August 22, 2018
Filing Date:
May 09, 2014
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D207/12; A61K31/402; A61K31/4025; A61K31/4439; A61K31/506; A61K31/5377; A61P3/04; A61P3/10; A61P43/00; C07D401/04; C07D401/14; C07D403/04; C07D403/14; C07D405/04; C07D405/14; C07D417/14
Domestic Patent References:
| JP2011513232A | ||||
| JP2000507216A |
Foreign References:
| WO2012032014A1 | ||||
| WO2012001107A1 | ||||
| US20130040928 |
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Akizawa
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Akizawa