Title:
PYRROLIDINYL UREA AND PYRROLIDINYL THIOUREA COMPOUNDS AS TRKA KINASE INHIBITORS
Document Type and Number:
Japanese Patent JP2017171672
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide agents for treating pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases comprising TrkA kinase inhibitors.SOLUTION: The invention provides compounds represented by formula I, where Rare each independently H or the like; X is O, S or NH; and ring C is a group having an imidazole ring.)SELECTED DRAWING: None
Inventors:
ALLEN SHELLEY
STEVEN W ANDREWS
BLAKE JAMES F
KEVIN R CONDROSKI
JULIA HAAS
LILY HUANG
JIANG YUTONG
TIMOTHY KERCHER
GABRIELLE R KOLAKOWSKI
SEO JEONGBEOB
STEVEN W ANDREWS
BLAKE JAMES F
KEVIN R CONDROSKI
JULIA HAAS
LILY HUANG
JIANG YUTONG
TIMOTHY KERCHER
GABRIELLE R KOLAKOWSKI
SEO JEONGBEOB
Application Number:
JP2017090432A
Publication Date:
September 28, 2017
Filing Date:
April 28, 2017
Export Citation:
Assignee:
ARRAY BIOPHARMA INC
International Classes:
C07D401/14; A61K31/4162; A61K31/4178; A61K31/422; A61K31/427; A61K31/4439; A61K31/497; A61P25/00; A61P29/00; A61P35/00; A61P43/00; C07D403/12; C07D403/14; C07D405/14; C07D409/04; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D491/048; C07D495/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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