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Title:
抗腫瘍薬としてのキナゾリン誘導体
Document Type and Number:
Japanese Patent JP2005511603
Kind Code:
A
Abstract:
The invention concerns quinazoline derivatives of Formula (I); wherein each of Q<1>, Q<2>, Z, R<1>, R<2>, R<3>, and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosin kinases.

Inventors:
Hennekin, Laurent Francois Andre
Kettle, Jason Grant
Pass, martin
Bradbury, Robert Hugh
Application Number:
JP2003542155A
Publication Date:
April 28, 2005
Filing Date:
October 31, 2002
Export Citation:
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Assignee:
AstraZeneca Activrag
International Classes:
A61K31/517; A61K31/5377; A61P35/00; A61P43/00; C07D239/94; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D411/12; C07D413/12; C07D413/14; C07D417/14; (IPC1-7): C07D239/94; A61K31/517; A61K31/5377; A61P35/00; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D409/12; C07D409/14; C07D411/12; C07D413/12; C07D417/14
Domestic Patent References:
JPH10508616A1998-08-25
JPH10505600A1998-06-02
JPH11508906A1999-08-03
JP2000504713A2000-04-18
JP2005512972A2005-05-12
JP3774438B22006-05-17
JP2005515176A2005-05-26
Foreign References:
WO1998050370A11998-11-12
WO1998002434A11998-01-22
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri