Title:
GABA-B受容体のアロステリックエンハンサーとしてのキノリン
Document Type and Number:
Japanese Patent JP2008517963
Kind Code:
A
Abstract:
The present invention relates to compounds of formula I wherein R1 to R6 are as described herein, which compounds are active at the GABAB receptor and can be used for the preparation of medicaments useful in the treatment of CNS disorders comprising anxiety and depression.
Inventors:
Marelub, Palique
Raffaello, Masziadri
Norcross, Roger David
Ratony, Asan
Thomas, Andrew William
Raffaello, Masziadri
Norcross, Roger David
Ratony, Asan
Thomas, Andrew William
Application Number:
JP2007538321A
Publication Date:
May 29, 2008
Filing Date:
October 25, 2005
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D215/18; A61K31/47; A61K31/4725; A61K31/4741; A61K31/496; A61K31/5377; A61K31/55; A61P1/04; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00; C07D215/20; C07D215/38; C07D401/04; C07D413/04; C07D491/056
Domestic Patent References:
| JP2002544197A | 2002-12-24 | |||
| JP2002371078A | 2002-12-26 | |||
| JPH0853419A | 1996-02-27 | |||
| JP2002544197A | 2002-12-24 | |||
| JP2002371078A | 2002-12-26 | |||
| JPH0853419A | 1996-02-27 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito