Title:
QUINOLINE DERIVATIVE PREPARATION AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JP3901832
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain the subject preparation having excellent bioabsorbability, excellent stability and low toxicity, useful for both immediate-type and delayed- type allergies and useful as an antiallergic agent by compounding a specific crystal as an active ingredient.
SOLUTION: This quinoline derivative preparation contains the β-type crystal and/or γ-type crystal of a quinoline derivative of the formula as an active ingredient. The β-type crystal and/or γ-type crystal of a quinoline derivative of the formula is obtained by recrystallizing the derivative of formula in ethanol as a recrystallization solvent and subsequently drying the obtained crystal under vacuum to remove the ethanol. The crystal can be obtained as the respective crystal forms or as a mixture of both the crystal forms. The preparation is preferably prepared in the form selected from capsules, coatings, coated tablets and sugar-coated tablets which have light-shielding properties.
Inventors:
Nobuyuki Kimura
Hideji Takagaki
Muratake Naoko
Hideji Takagaki
Muratake Naoko
Application Number:
JP6290798A
Publication Date:
April 04, 2007
Filing Date:
March 13, 1998
Export Citation:
Assignee:
Dainippon Ink and Chemicals Co., Ltd.
International Classes:
A61K31/4704; C07D215/38; A61K9/16; A61K9/28; A61K9/48; A61K31/47; A61P37/08; C07B63/00; (IPC1-7): A61K31/47; A61K9/28; A61K9/48; C07B63/00; C07D215/38
Domestic Patent References:
| JP9255659A | ||||
| JP4346929A |
Foreign References:
| WO1997039752A1 |
Attorney, Agent or Firm:
Kono Tsuyo