Title:
誘導型一酸化窒素シンターゼ抑制剤として有用なキノロン類
Document Type and Number:
Japanese Patent JP2009529496
Kind Code:
A
Abstract:
The present invention relates to novel quinolones of Formula I that inhibit inducible NOS synthase together with methods of synthesizing and using the compounds including methods for inhibiting or modulating nitric oxide synthesis and/or lowering nitric oxide levels in a patient by administering the compounds for the treatment of disease.
Inventors:
Jeffrey Earl Ropp
Celine Bonff
Nicholas di smith
Andrew Kay Lindstrom
Stewart A. NOBLE
Christian A. Hassig
Joseph E. Payne
Hui Xuan
Xiao Hong Chen
Sergio G. Duron
Celine Bonff
Nicholas di smith
Andrew Kay Lindstrom
Stewart A. NOBLE
Christian A. Hassig
Joseph E. Payne
Hui Xuan
Xiao Hong Chen
Sergio G. Duron
Application Number:
JP2008556576A
Publication Date:
August 20, 2009
Filing Date:
February 23, 2007
Export Citation:
Assignee:
Calypsis Incorporated
International Classes:
A61K31/4704; A61K31/4709; A61K31/497; A61K31/5377; A61P1/02; A61P1/04; A61P3/10; A61P7/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/04; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P25/04; A61P25/06; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/22; A61P37/06; A61P37/08; A61P43/00; C07D215/22; C07D401/12; C07D405/12; C07D407/14; C07D409/12; C07D413/12; C07D413/14; C07D417/12; C07D417/14
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto