Title:
ＲＯＲガンマ（ＲＯＲγ）モジュレーター
Document Type and Number:
Japanese Patent JP6754778
Kind Code:
B2
Abstract:
The present invention relates to compounds according to Formula I :
or a pharmaceutically acceptable salt thereof wherein the variables have the meanings defined in the claims. The compounds can be used as inhibitors of ROR³ and are useful for the treatment of ROR³ mediated diseases.
Inventors:
Callus, Joseph Maria Geraldas Barbara
De Kinpe, Bella
Thunder Bernardas, Nabuls
De Kinpe, Bella
Thunder Bernardas, Nabuls
Application Number:
JP2017563240A
Publication Date:
September 16, 2020
Filing Date:
June 03, 2016
Export Citation:
Assignee:
Reed Pharma Holding B.V.
International Classes:
C07C311/46; A61K31/167; A61K31/18; A61K31/223; A61K31/277; A61K31/337; A61K31/341; A61K31/351; A61K31/381; A61K31/40; A61K31/404; A61K31/415; A61K31/42; A61K31/426; A61K31/427; A61K31/433; A61K31/4365; A61K31/44; A61K31/4402; A61K31/4406; A61K31/443; A61K31/445; A61K31/4453; A61K31/451; A61K31/47; A61K31/472; A61K31/495; A61K31/5375; A61K31/5377; A61K31/538; A61K31/55; A61K45/00; A61P1/04; A61P5/14; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P33/02; A61P37/06; A61P43/00; C07C317/50; C07D207/06; C07D209/08; C07D211/16; C07D211/26; C07D211/58; C07D211/60; C07D213/40; C07D213/71; C07D213/75; C07D213/82; C07D215/08; C07D217/06; C07D223/16; C07D231/40; C07D241/04; C07D261/08; C07D261/14; C07D265/34; C07D265/36; C07D277/46; C07D285/135; C07D295/13; C07D295/192; C07D305/08; C07D307/14; C07D307/52; C07D309/14; C07D333/24; C07D333/36; C07D405/12; C07D417/04; C07D495/04
Foreign References:
| WO2013171729A1 | ||||
| WO2013029338A1 | ||||
| WO2014125426A1 | ||||
| US4146637 |
Other References:
ACS Medicinal Chemistry Letters ,2014年,5(1),65-68
ACS Medicinal Chemistry Letters ,2015年,6(7),787-792
ACS Medicinal Chemistry Letters ,2015年,6(7),787-792
Attorney, Agent or Firm:
Mitsuo Matsui
Hiroshi Murakami
Hiroshi Murakami