Title:
RADIOACTIVE DIAGNOSTIC AGENT LABELLED WITH TECNETIUM 99M AND PRODUCTION THEREOF
Document Type and Number:
Japanese Patent JPS542343
Kind Code:
A
Abstract:
1508900 Radiodiagnostic compositions UNION CARBIDE CORP 28 Aug 1975 [29 Aug 1974] 12642/76 Divided out of 1508899 Heading A5B [Also in Division C3] A stable non - radioactive macroaggregated albumin carrier comprising human serum albumin and stannous ion chelated with tartrate, the carrier having a pH from 5 to 6 and being in the form of particles from 3 to 150 microns in diameter is prepared by (a) contacting a saline solution with a sufficient amount of an acid which is non - oxidising to tin under the conditions employed to adjust the pH of the solution from 2 to 6 (b) introducing stannous tartrate and human serum albumin into the solution (c) adding sodium hydroxide to adjust the pH from 5 to 6 and (d) heating to macroaggregate the albumin. Preferably a preservative is added to the tartrate solution e.g. sodium ethyl mercurithio calicylate and methyl or propyl phydroxybenzoates. The carrier may be used to support sodium pentechinate containing 99m Tc for radiodiagnostic techniques.
Inventors:
PIKUTAA JIYOZEFU MORINSUKII
JIYOZEFU AASAA UIRUCHIEUSUKI
JIYOZEFU AASAA UIRUCHIEUSUKI
Application Number:
JP4181778A
Publication Date:
January 09, 1979
Filing Date:
April 11, 1978
Export Citation:
Assignee:
UNION CARBIDE CORP
International Classes:
A61K51/00; A61K33/24; A61K51/08; A61K51/12; G01N33/60; (IPC1-7): A61K29/00; A61K43/00