Title:
ランダムバイオオリゴマーライブラリー、その合成方法、およびその使用方法
Document Type and Number:
Japanese Patent JP3552718
Kind Code:
B2
Abstract:
The instant invention provides a library of bio-oligomers of defined size and known composition, in which the library contains all of the possible sequences of the bio-oligomers, and a method of synthesis thereof. The bio-oligomers of the library may be peptides, nucleic acids, or a combination of the foregoing. The instant invention also provides methods to identify bio-oligomers from a library that demonstrate desired characteristics such as binding, bioactivity and catalytic activity. Thus the instant invention provides a unique and powerful method to identify a useful bio-oligomer sequences from a library more quickly than current state-of-the-art technology allows. Effector molecules for use in treatment or diagnosis of disease are also provided.
Inventors:
Lamb, kit sang
Salmon, Sydney E.
Ruby, Victor Jay.
Hirsch, Evan, M.
Al-Obaydi, Fahd
Salmon, Sydney E.
Ruby, Victor Jay.
Hirsch, Evan, M.
Al-Obaydi, Fahd
Application Number:
JP51265091A
Publication Date:
August 11, 2004
Filing Date:
July 01, 1991
Export Citation:
Assignee:
The Arizona Board of Regents for the University of Arizona
International Classes:
A61K38/00; A61K38/02; A61K38/22; A61K39/00; A61K47/48; C07H21/00; C07K1/04; C07K1/06; C07K7/06; C07K7/08; C07K14/575; C07K14/70; C07K14/705; C07K14/82; C07K16/00; C07K17/00; C07K17/02; C07K17/08; C12N9/00; C12N15/00; C12N15/09; C12N15/10; C12P21/02; C12Q1/00; C12Q1/68; G01N33/53; G01N33/531; G01N33/545; G01N33/68; C12R1/91; C40B40/06; C40B40/10; (IPC1-7): C07K17/08; C07K1/04; C07K1/06; C12N15/00; C12Q1/68; G01N33/68
Domestic Patent References:
| JP1149800A | ||||
| JP52156819A | ||||
| JP61275296A |
Foreign References:
| WO1989010931A1 | ||||
| WO1989010977A1 | ||||
| WO1990015070A1 | ||||
| WO1989005305A1 |
Other References:
14th International Congress of Biochem.(1998), Vol.5, Abstruct FR:013
Attorney, Agent or Firm:
Yusuke Hiraki