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Title:
REACTIVE CRYSTALLIZATION METHOD FOR IMPROVING PARTICLE SIZE
Document Type and Number:
Japanese Patent JP2002028475
Kind Code:
A
Abstract:

To provide a method for simultaneously executing a chemical reaction and controlled crystallization of products by using an impinging fluid jet stream containing a reactant which can manufacture the products having desired particle size characteristics.

One or more jet stream 1 of a solution of a first reactive intermediate in a first solvent and one or more jet stream 2 of a solution of a second reactive intermediate in a second solvent are made to collide and mix with each other at an impulse point 3 so as to generate violent turbulence in the temperature and pressure conditions which enable reaction to be caused to generate products.


Inventors:
AM ENDE DAVID JON
CRAWFORD THOMAS CHARLES
WESTON NEIL PHILIP
Application Number:
JP2001153592A
Publication Date:
January 29, 2002
Filing Date:
May 23, 2001
Export Citation:
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Assignee:
PFIZER PROD INC
International Classes:
B01D9/00; B01D9/02; B01F5/02; C07D487/22; B01J14/00; B01J19/00; B01J19/18; B01J19/26; C07B61/00; C07C51/41; C07C51/43; C07D403/10; C07D417/12; C07D471/08; C07D521/00; A61K9/16; B01F7/00; B01F13/00; (IPC1-7): B01J19/00; C07D403/10; C07D417/12; C07D487/22
Attorney, Agent or Firm:
Hiroshi Kobayashi (1 outside)