Title:
自己免疫疾患用の試薬および治療方法
Document Type and Number:
Japanese Patent JP2005526501
Kind Code:
A
Abstract:
The invention concerns treatment methods using anti-CD22 monoclonal antibodies with unique physiologic properties. In particular, the invention concerns methods for the treatment of B-cell malignancies and autoimmune diseases by administering an effective amount of a blocking anti-CD22 monoclonal antibody specifically binding to the first two Ig-like domains, or to an epitope within the first two Ig-like domains of native human CD22 (hCD22).
Inventors:
Tedder, Thomas F
Application Number:
JP2003571424A
Publication Date:
September 08, 2005
Filing Date:
February 21, 2003
Export Citation:
Assignee:
Duke University
International Classes:
C12N15/09; A61B5/055; A61K39/395; A61P35/00; A61P35/02; A61P37/02; C07K16/28; C07K16/42; C12N15/13; C12P21/08; G01N24/08; (IPC1-7): C12N15/09; A61K39/395; A61P35/00; A61P35/02; A61P37/02
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo