Title:
Reduction of interference of the white corpuscles in noncompetitive immunological assay
Document Type and Number:
Japanese Patent JP6054745
Kind Code:
B2
Abstract:
The invention is directed to methods and devices for reducing interference from leukocytes in an analyte immunoassay, and in particular in non-competitive immunoassays. In one embodiment, the invention is to a method comprising the steps of (a) amending a biological sample such as a whole blood sample with sacrificial beads; and (b) performing a non-competitive immunoassay on the amended sample to determine the concentration of said analyte in said sample. Preferably, the sample is amended with IgG-coated sacrificial beads.
Inventors:
Campbell, John Lewis Emerson
Moss, Adam Roger
Davis, Graham
Moss, Adam Roger
Davis, Graham
Application Number:
JP2012540007A
Publication Date:
December 27, 2016
Filing Date:
November 17, 2010
Export Citation:
Assignee:
Abbott Point of Care, Inc.
International Classes:
G01N33/543; G01N27/00; G01N27/327; G01N27/416; G01N29/02; G01N33/53
Domestic Patent References:
| JP8062214A | ||||
| JP2007505319A |
Foreign References:
| WO2008052338A1 |
Other References:
M.J.Hickey and P.Kubus, Intravascular immunity:the host-pathogen encounter in blood vessels, Nature Reviews Immunology, 2009年 5月, Vol.9, pp.364-375
Attorney, Agent or Firm:
Asamura patent office