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Title:
血管形成の調節
Document Type and Number:
Japanese Patent JP6312326
Kind Code:
B2
Abstract:
The invention provides methods for treating pathological conditions that can be improved by providing angiogenesis. The invention is generally directed to provide angiogenesis by administering cells that express and/or secrete one or more pro-angiogenic factors. The invention is also directed to drug discovery methods to screen for agents that modulate the ability of the cells to express and/or secrete one or more pro-angiogenic factors. The invention is also directed to cell banks that can be used to provide cells for administration to a subject, the banks comprising cells having desired levels of expression and/or secretion of one or more pro-angiogenic factors.

Inventors:
Juliana Megan Woda
Anthony E. Tin
Nicholas A. Lehman
Application Number:
JP2015044246A
Publication Date:
April 18, 2018
Filing Date:
March 06, 2015
Export Citation:
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Assignee:
ABT Holding Company
International Classes:
C12N5/07; A61K35/12; A61K35/545; A61P9/00; C12Q1/02; G01N33/15; G01N33/50; G01N33/53
Domestic Patent References:
JP2013500012A
JP2009537127A
JP2003506075A
JP2009523847A
JP2008044965A
Other References:
The Journal of Clinical Investigation,2008年,Vol.118, No.2,p.505-514
OsteoArthritis and Cartilage,2004年,Vol.12,p.683-691
Cancer Research,2005年,Vol.65, No.17,p.7707-7716
Journal of Tissue Engineering and Regenerative Medicine,2007年,Vol.1,p.51-59
Respiratory Research (2006) Vol.7, p.82 (pp.1-13)
Eur. J. Cancer (2006) Vol.42, pp.768-778
Attorney, Agent or Firm:
Takeshi Oshio