Title:
グルココルチコイド受容体発現の調節
Document Type and Number:
Japanese Patent JP2009508527
Kind Code:
A
Abstract:
Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides which have particular in vivo properties, targeted to nucleic acids encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for treatment of diseases are provided.
Inventors:
Monia, Brett Pea
Robert matsukei
Flyer, Susan M
Banoto, Sanjay
Watatsu, Linetsuta
Robert matsukei
Flyer, Susan M
Banoto, Sanjay
Watatsu, Linetsuta
Application Number:
JP2008532324A
Publication Date:
March 05, 2009
Filing Date:
September 19, 2006
Export Citation:
Assignee:
Jiyoung Son and Ji Jong Son Pharma Machinery Research and Development LLC
International Classes:
C12N15/09; A61K31/7088; A61K48/00; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; C12N5/10; C12N15/113
Domestic Patent References:
| JP2005525829A | 2005-09-02 |
Foreign References:
| US20050203042A1 | 2005-09-15 |
Other References:
JPN6012002897; Ｄｉａｂｅｔｅｓ， 第５４巻， ２００５年６月， １８４６-１８５３ページ
Attorney, Agent or Firm:
Patent business corporation Odashima patent office