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Title:
低分子量GTPアーゼのRapファミリーに属するタンパク質のグアニンヌクレオチド交換因子の制御
Document Type and Number:
Japanese Patent JP2006525300
Kind Code:
A
Abstract:
The invention relates generally to the methods of treating brain diseases and compounds for treating brain diseases, and more specifically relates to using compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat diseases of the brain, such as Alzheimer's and Schizophrenia.

Inventors:
McAfee, Ian
Breslin, Catherine
Kewney, Justin, Peter
Mackenzie, Simon, John
Coleman, Anne
Gibson, Lucian, Charles, Donald
Hammond, Stephen
McFarlane, Morag
Application Number:
JP2006506212A
Publication Date:
November 09, 2006
Filing Date:
May 04, 2004
Export Citation:
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Assignee:
Scottish Biomedical Limited
International Classes:
A61K45/00; A61K31/122; A61K31/136; A61K31/404; A61K31/4184; A61K31/426; A61K31/427; A61K31/428; A61K31/505; A61K31/519; A61K31/5377; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/28; G01N33/68
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio