PURPOSE: A remedy for hyperlipemia having strongly inhibitory action on cholesterol biosynthesis and low toxicity, containing a specific antibiotic or a salt thereof as an active ingredient.
CONSTITUTION: A remedy containing antibiotic 1233A shown by formula I and reduced substance 1233A shown by formula II or a salt thereof as active ingredients. It is necessary to inhibit cholesterol biosynthesis to prevent and to treat hypercholesterolemia readily causing arteriosclerosis and the compound shown by the formula I, metabolite of microorganism, has strongly inhibitory action on cholesterol biosynthesis and is useful as a remedy for hyperlipemia. The compounds shown by the formulas I and II are preferably prepared into injection, oral drug, rectal absorption agent, etc., with respect to their physical properties.
KODA HIROSHI
IWAI YUZURU
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