Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
REMOVAL OF TAXANE-TYPE DITERPENES
Document Type and Number:
Japanese Patent JP2000044523
Kind Code:
A
Abstract:

To inexpensively obtain a taxane-type compound while maintaining an environment by carrying out extraction, isolation and purification using the needle leaf part of Taxus cuspidata Sieb et Zucc.

A needle leaf part of Taxus cuspidata Sieb et Zucc is extended, for example, with an organic solvent (preferably methanol, ethyl acetate, n- hexane or the like) and the obtained extracted solution is treated with an acid and/or a base and then fractionated by liquid chromatography to take out taxol(s), cephalomanin(s) being a precursor (intermediate) for taxol, a taxinin compound of formula I, a taxine compound of formula II, etc. The compound of formula I and the compound of formula II are new compounds. Consequently a large amount of taxane-type diterpenes capable of dealing with an increase in demand can be taken out while maintaining an environment.


Inventors:
ANDO MASAYOSHI
Application Number:
JP21450798A
Publication Date:
February 15, 2000
Filing Date:
July 29, 1998
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOBE TENNENBUTSU KAGAKU KK
International Classes:
C07D305/14; C07C67/48; C07C69/33; C07C227/40; C07C229/34; (IPC1-7): C07C229/34; C07C67/48; C07C69/33; C07C227/40; C07D305/14
Attorney, Agent or Firm:
Kenzo Hara