NEW MATERIAL:A riboflavin derivative expressed by the formula (M is alkaline metal atom).
USE: Having vitamin B2 acid activity, useful in the field of medicines, etc., effectively used as a controlling agent for red tide and capable of exhibiting a high solubility in water.
PREPARATION: Vitamin B2 acid is neutralized with, e.g., sodium or potassium hydroxide, to afford the compound expressed by the formula. The vitamin B2 acid is normally used as an aqueous solution in 0.1-100mml/l concentration and the reaction temperature is ambient temperature to 80°C. As a specific example, the vitamin B2 acid is dissolved in water, concentrated in a concentrator and then placed in a reactor having a stirrer. An aqueous solution of sodium hydroxide is subsequently added at ambient temperature and pH7.53 in a state of shielded light while stirring. After the addition, reaction is carried out for 3-hr. The reaction mixture is concentrated and filtered and the filtrate is freeze- dried in a freeze-dryer to provide sodium salt of the vitamin B2 acid.
JP6653663 | Inorganic organic hybrid compound |
JPH06279445 | CANCER METASTASIS SUPPRESSOR |
JPS5281086 | COMPOSITE MATERIALS |
TAKAHASHI MITSUNAO
MATOBA YASUHIRO
YAMAUCHI SHIN
SADA NORIMASA
TODA TOKU