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Title:
RIBONUCLEASE RESISTANT RNA PREPARATION AND UTILIZATION
Document Type and Number:
Japanese Patent JP2009131272
Kind Code:
A
Abstract:

To provide nuclease-resistant nucleic acids in general and ribonuclease-resistant RNAs in particular.

Methods of making and using such nucleic acids are disclosed. Nucleic acid standards comprising nuclease-resistant nucleic acid segments comprising a sequence coding a standard nucleic acid are disclosed, wherein the nucleic acid segments are protected from nuclease decomposition upon cultivation for 5 minutes or more at a room temperature in normal human serum, and problems are solved by the nucleic acid standards.


Inventors:
DUBOIS DWIGHT B
WINKLER MATTHEW M
PASLOSKE BRITTAN L
DAVID BROWN
Application Number:
JP2009055769A
Publication Date:
June 18, 2009
Filing Date:
March 09, 2009
Export Citation:
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Assignee:
ASURAGEN INC
CENETRON DIAGNOSTICS LLC
International Classes:
C12N15/09; A61K9/127; A61K9/50; A61K35/76; A61K39/00; A61K47/32; A61K47/36; A61K47/44; A61K48/00; C07K14/01; C12N7/04; C12N15/10; C12N15/40; C12N15/86; C12N15/88; C12P19/34; C12Q1/68; C12Q1/70
Attorney, Agent or Firm:
Hidesaku Yamamoto