Title:
SALTS OF 7-CYCLOPENTYL-2-(5-PIPERAZIN-1-YL-PYRIDIN-2-YLAMINO)-7H-PYRROLO[2,3-D]PYRIMIDINE-6-CARBOXYLIC ACID DIMETHYLAMIDE AND PROCESSES OF MAKING THE SAME
Document Type and Number:
Japanese Patent JP2017057203
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compounds that inhibit cyclin dependent kinase activity and are useful in treating various cancers including leukemia, and pharmaceutical compositions comprising the compounds.SOLUTION: This invention relates to succinate salts of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide represented by formula (II); and pharmaceutical compositions comprising the compounds.SELECTED DRAWING: None
Inventors:
JOHN VINCENT CALIENNI
CHEN GUANG PEI
GONG BAOQING
PRASAD KOTESWARA KAPA
VISHAL SAXENA
CHEN GUANG PEI
GONG BAOQING
PRASAD KOTESWARA KAPA
VISHAL SAXENA
Application Number:
JP2016202167A
Publication Date:
March 23, 2017
Filing Date:
October 14, 2016
Export Citation:
Assignee:
NOVARTIS AG
ASTEX THERAPEUTICS LTD
ASTEX THERAPEUTICS LTD
International Classes:
C07D487/04; A61K31/519; A61P35/00; A61P35/02; A61P43/00
Foreign References:
| WO2010020675A1 | 2010-02-25 |
Other References:
芦澤 一英、他, 医薬品の多形現象と晶析の科学, JPN7015003233, 20 September 2002 (2002-09-20), pages 305 - 317, ISSN: 0003514124
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Saori Oga
Hakoda Mitsuru
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Saori Oga
Hakoda Mitsuru
Yasuhito Suzuki