Title:
SAPONIN AS TRITERPENE, AND METHOD OF SYNTHESIS AND USE THEREOF
Document Type and Number:
Japanese Patent JP2015134793
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a saponin compound analogous to QS-21 currently favored in anticancer and antiviral vaccines.SOLUTION: This invention relates to a compound represented by a formula X, where ^^^ is a single bond or a double bond; W is Me, -CHO or the like; V is hydrogen or the like; Y is CH2, -O- or the like; and Z is a specific carbohydrate domain.
Inventors:
DAVID GIN
MICHELLE ADAMS
DENG KAI
NICHOLAS PERL
ANNIE WON
PHILIP LIVINGSTON
GOVIND RAGUPATHI
MICHELLE ADAMS
DENG KAI
NICHOLAS PERL
ANNIE WON
PHILIP LIVINGSTON
GOVIND RAGUPATHI
Application Number:
JP2015038239A
Publication Date:
July 27, 2015
Filing Date:
February 27, 2015
Export Citation:
Assignee:
SLOAN KETTERING INST CANCER
International Classes:
C07J63/00; A61K31/569; A61K31/57; A61K39/00; A61K39/39; A61P31/00; A61P35/00
Foreign References:
| CN101322734A | 2008-12-17 |
Other References:
BLIARD,C. ET AL, TETRAHEDRON LETTERS, vol. 35, no. 33, JPN6016007573, 1994, pages 6107 - 6108
HAN,J. ET AL, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. Vol.44, JPN6016007574, 2007, pages 430 - 438
YUODVIRSHIS,A.M. ET AL, CHEMISTRY OF NATURAL COMPOUNDS, vol. 2, no. 6, JPN6016007575, 1966, pages 331 - 334
BLIARD,C. ET AL, TETRAHEDRON LETTERS, vol. 35, no. 33, JPN6016007573, 1994, pages 6107 - 6108
HAN,J. ET AL, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. Vol.44, JPN6016007574, 2007, pages 430 - 438
YUODVIRSHIS,A.M. ET AL, CHEMISTRY OF NATURAL COMPOUNDS, vol. 2, no. 6, JPN6016007575, 1966, pages 331 - 334
HAN,J. ET AL, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. Vol.44, JPN6016007574, 2007, pages 430 - 438
YUODVIRSHIS,A.M. ET AL, CHEMISTRY OF NATURAL COMPOUNDS, vol. 2, no. 6, JPN6016007575, 1966, pages 331 - 334
BLIARD,C. ET AL, TETRAHEDRON LETTERS, vol. 35, no. 33, JPN6016007573, 1994, pages 6107 - 6108
HAN,J. ET AL, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. Vol.44, JPN6016007574, 2007, pages 430 - 438
YUODVIRSHIS,A.M. ET AL, CHEMISTRY OF NATURAL COMPOUNDS, vol. 2, no. 6, JPN6016007575, 1966, pages 331 - 334
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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