Title:
色素沈着の予防又は改善剤のスクリーニング法とそのスクリーニング法によって見出された色素沈着の予防又は改善剤
Document Type and Number:
Japanese Patent JP5896398
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a method for preventing or ameliorating tissue pigmentation.SOLUTION: The method for preventing or ameliorating tissue pigmentation is established by finding that Wnt1 expression inhibitor, Wnt3a expression inhibitor, Wnt7a expression inhibitor, Wnt7b expression inhibitor, Wnt10b expression inhibitor and Norrin expression inhibitor being substances for suppressing Wnt signaling pathway exhibit remarkable preventing and ameliorating effect on tissue pigmentation.
Inventors:
Takaaki Yamada
Yasuji Hasegawa
Tsutomu Sakata
Yasuji Hasegawa
Tsutomu Sakata
Application Number:
JP2011207060A
Publication Date:
March 30, 2016
Filing Date:
September 22, 2011
Export Citation:
Assignee:
Nippon Menard Cosmetics Co., Ltd.
International Classes:
A61K48/00; A61K8/60; A61K31/7088; A61K31/7105; A61P17/00; A61Q19/02; G01N33/15; G01N33/50
Other References:
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Pigment cell & melanoma research,2009年,Vol.22, No.6,p.724-739
Cell,2011年 6月10日,Vol.145, No.6,p.941-955
Proc. Natl. Acad. Sci. U.S.A.,2000年,Vol.97, No.18,p.10050-10055
Pigment cell & melanoma research,2009年,Vol.22, No.6,p.724-739
Cell,2011年 6月10日,Vol.145, No.6,p.941-955
Proc. Natl. Acad. Sci. U.S.A.,2000年,Vol.97, No.18,p.10050-10055