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Title:
【発明の名称】組織プラスミノーゲン活性化因子プロ配列を使用するグリコシル化タンパク質の分泌
Document Type and Number:
Japanese Patent JP2002511264
Kind Code:
A
Abstract:
DNA constructs, host cells and production methods are disclosed for the expression and recovery of polypeptides, especially those altered to have one or more glycosylation sites added or deleted. The DNA constructs, host cells and methods provided herein employ a DNA segment corresponding to a mammalian tissue plasminogen activator signal and/or pro peptide.

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Inventors:
Ashkenazi, Avi, J.
Bellman, Philip, W.
Bluesaw, david
Echeberry, Tina
Application Number:
JP2000543607A
Publication Date:
April 16, 2002
Filing Date:
April 14, 1999
Export Citation:
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Assignee:
GENENTECH,INC.
International Classes:
C12N15/09; C07K14/705; C07K14/715; C12N5/10; C12N9/72; C12N15/12; C12P21/02; (IPC1-7): C12N15/09; C07K14/705; C12N5/10; C12N9/72; C12P21/02
Attorney, Agent or Firm:
Yoshitaka Sonoda (1 outside)



 
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