Title:
陰イオン性リン脂質およびアミノリン脂質に結合する選択された抗体およびデュラマイシンペプチド、ならびにウイルス感染の処置におけるそれらの使用
Document Type and Number:
Japanese Patent JP4827411
Kind Code:
B2
Abstract:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Inventors:
Soap, Philip E.
Swords, Melina M.
Juan, Shan Min
Hey, Jin
Orchid, sofia
Swords, Melina M.
Juan, Shan Min
Hey, Jin
Orchid, sofia
Application Number:
JP2004521771A
Publication Date:
November 30, 2011
Filing Date:
July 15, 2003
Export Citation:
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
A61K39/395; A61K45/00; A61P3/04; A61P3/10; A61P5/14; A61P7/04; A61P7/06; A61P9/10; A61P15/08; A61P17/00; A61P17/10; A61P19/02; A61P19/06; A61P27/02; A61P27/06; A61P29/00; A61P31/10; A61P31/12; A61P31/22; A61P33/00; A61P35/00; A61P37/02; A61P43/00; C07K16/18; C07K16/28; C07K16/44
Domestic Patent References:
| JPH0892124A | 1996-04-09 | |||
| JP2002520297A | 2002-07-09 |
Foreign References:
| WO2001066785A1 | 2001-09-13 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita