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Title:
選択的に置換されたキノリン化合物
Document Type and Number:
Japanese Patent JP6420878
Kind Code:
B2
Abstract:
Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Inventors:
Carlson, Eric
Hansen, Hans
Mackey, matthew
Schiller, Shawn
Ogawa, Chikako
Davis, Heather
Pea, Atsushi
Hawkins, Lynn
Sari, sari
Application Number:
JP2017193598A
Publication Date:
November 07, 2018
Filing Date:
October 03, 2017
Export Citation:
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Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D413/04; C07D413/14; C07D417/14; C07D451/04
Domestic Patent References:
JP6223563B2
JP2013028588A
JP2005132834A
JP2007524615A
JP2000510865A
Foreign References:
CN1528748A
Other References:
Joint Bone Spine,2010年,Vol.77, No.1,pp.4-5,ISSN:1297-319X, DOI:10.1016/j.jbspin.2009.09.007
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito