To provide a suture thread composition or a staple composition, capable of capturing a reinforcing material, and capable of reducing thereby the risk of leakage.
A wound closure device contains a first reactive component 4, and the reinforcing material contains a second complementary reactive component, in a self-sealing implant object provided with the at least one wound closure device and the reinforcing material. A system includes a process for arranging a buttress containing the first reactive component 4 on a tissue, a process for shooting at least one staple containing the second complementary reactive component, from a stapler, and for bringing the at least one staple into contact with the buttress, and a process for starting a chemical reaction.