Title:
架橋ヘモグロビンからの未修飾ヘモグロビンの分離
Document Type and Number:
Japanese Patent JP3950477
Kind Code:
B2
Abstract:
A method for separating unmodified hemoglobin from cross-linked hemoglobin in a hemoglobin solution. The method involves contacting the hemoglobin solution with a least one dissociating agent to form a dissociation solution wherein unmodified tetrameric hemoglobin is dissociated to form hemoglobin dimers. The hemoglobin dimers are then separated from the dissociation solution, while retaining the cross-linked hemoglobin in the dissociation solution.
Inventors:
Wright, William Earl.
Goril, Maria Es.
Lassetti, Anthony Jay.
Houtchens, Robert A.
Goril, Maria Es.
Lassetti, Anthony Jay.
Houtchens, Robert A.
Application Number:
JP50161097A
Publication Date:
August 01, 2007
Filing Date:
June 05, 1996
Export Citation:
Assignee:
Biopure Corporation
International Classes:
C07K1/14; C07K14/805
Domestic Patent References:
| JP3502580A |
Attorney, Agent or Firm:
Yoshinori Hosoda