Title:
血清群B髄膜炎菌のためのアジュバント添加ワクチン
Document Type and Number:
Japanese Patent JP2013522287
Kind Code:
A
Abstract:
An immunogenic composition comprises (i) an immuno stimulatory oligonucleotide and a polycationic polymer, wherein the oligonucleotide and the polymer ideally associate with each other to form a complex, and (ii) a meningococcal serogroup B antigen. In most embodiments, the composition does not include an aluminium salt and does not include an oil-in-water emulsion.
Inventors:
Pallaoro, Michele
Ohergan, derek
Lapuoli, Reno
Ohergan, derek
Lapuoli, Reno
Application Number:
JP2012557654A
Publication Date:
June 13, 2013
Filing Date:
March 18, 2011
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K39/095; A61K39/05; A61K39/08; A61K39/09; A61K39/10; A61K39/116; A61K39/13; A61K39/29; A61K39/295; A61K39/39; A61P31/04; A61P31/12; C07K7/06; C07K14/22; C12N15/113
Domestic Patent References:
| JP2006516608A | 2006-07-06 | |||
| JP2001500540A | 2001-01-16 |
Foreign References:
| WO2009104097A2 | 2009-08-27 |
Other References:
JPN6014052174; Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． ＵＳＡ， ２００６， Ｖｏｌ．１０３， Ｎｏ．２９， ｐｐ．１０８３４-１０８３９
JPN6014052175; Ｓｃａｎｄ． Ｊ． Ｉｍｍｕｎｏｌ．， ２００９， Ｖｏｌ．６９， Ｎｏ．３， ｐｐ．１９４-２０２
JPN6014052176; Ｊ． Ｃｈｒｏｍａｔｏｇｒ． Ｂ， Ａｎａｌｙｔ． Ｔｅｃｈｎｏｌ． Ｂｉｏｍｅｄ． Ｌｉｆｅ Ｓｃｉ．， ２００５， Ｖｏｌ．８２２， Ｎｏ．１-２， ｐｐ．２６３-２７０
JPN6014052177; Ｖａｃｃｉｎｅ， ２００６， Ｖｏｌ．２４， Ｎｏ．２６， ｐｐ．５４６１-５４７２
JPN6014052175; Ｓｃａｎｄ． Ｊ． Ｉｍｍｕｎｏｌ．， ２００９， Ｖｏｌ．６９， Ｎｏ．３， ｐｐ．１９４-２０２
JPN6014052176; Ｊ． Ｃｈｒｏｍａｔｏｇｒ． Ｂ， Ａｎａｌｙｔ． Ｔｅｃｈｎｏｌ． Ｂｉｏｍｅｄ． Ｌｉｆｅ Ｓｃｉ．， ２００５， Ｖｏｌ．８２２， Ｎｏ．１-２， ｐｐ．２６３-２７０
JPN6014052177; Ｖａｃｃｉｎｅ， ２００６， Ｖｏｌ．２４， Ｎｏ．２６， ｐｐ．５４６１-５４７２
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita