Title:
シアル酸誘導体
Document Type and Number:
Japanese Patent JP4094662
Kind Code:
B2
Abstract:
Sialic acid derivatives represented by the following general formula: wherein R<1> represents a residue of a steroid compound excluding cholestane and cholestene residues, R<2> represents hydrogen or methyl group, R<3> represents a C1-C6 alkyl group and other, R<4> represents hydrogen or acyl group, R<5> represents a group of R<15>O- (R<15> represents a C2-C7 acyl group and other), and X represents oxygen or sulfur atom, and their derivatives. These derivatives have activating effect on choline acetyltransferase activity in the chlonergic neurons, and are useful for preventive and therapeutic treatment of dementia, memory disorder, peripheral nervous disorder and so forth.
Inventors:
Haruki Yuuki
Naoko Ando
Tetsuo Naohara
Kenichi Saito
Tomoko Yugami
Naoko Ando
Tetsuo Naohara
Kenichi Saito
Tomoko Yugami
Application Number:
JP50373197A
Publication Date:
June 04, 2008
Filing Date:
June 21, 1996
Export Citation:
Assignee:
Mitsubishi Chemical Corporation
International Classes:
C07J17/00; A61K31/704; A61P25/28; C07H15/04; C07H15/12; C07J41/00; G01N33/50
Domestic Patent References:
| JP6363697A | ||||
| JP62209094A | ||||
| JP61243096A | ||||
| JP3778372B2 | ||||
| JP1190693A | ||||
| JP5105694A | ||||
| JP592991A | ||||
| JP381287A |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes
Masazumi Imamura
Masazumi Imamura