Title:
SIALIDASE INHIBITOR
Document Type and Number:
Japanese Patent JP2008285448
Kind Code:
A
Abstract:
To provide a new sialidase inhibitor effective for inhibiting the activity of sialidase of influenza virus, etc.
The sialidase inhibitor is composed of a derivative obtained by introducing a substituent having an aromatic ring on the 9-site of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA) and expressed by formula (R is a substituent having an aromatic ring) or a pharmacologically permissible salt of the derivative.
Inventors:
NISHIMURA SHINICHIRO
HINO HIROSHI
HINO HIROSHI
Application Number:
JP2007133705A
Publication Date:
November 27, 2008
Filing Date:
May 21, 2007
Export Citation:
Assignee:
UNIV HOKKAIDO
International Classes:
A61K31/351; A61K31/4192; A61K31/58; A61P31/12; A61P43/00; C07D309/30; C07D405/06; C07J17/00
Other References:
JPN6012041414; Ｇｉｊｓｂｅｒｔｕｓ Ｔ． Ｊ． ｖａｎ ｄｅｒ Ｈｏｒｓｔ: Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ , 19900705, ｖｏｌ．２６５， Ｎｏ．１９， ｐｐ．１０８０１-１０８０４
Attorney, Agent or Firm:
Akira Shimoda
Kenichiro Akao
Naoto Koyama
Kenichiro Akao
Naoto Koyama
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