Title:
核酸配列を特性決定するための単一分子シーケンシング及び固有の分子識別子
Document Type and Number:
Japanese Patent JP7208230
Kind Code:
B2
Abstract:
Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.
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Inventors:
Apte, Zaccary
Rich Man, Jessica
Armonaside, Daniel
Morales, Eduardo
Leon, Luis
Byrd, Sarah W.
Ugarde, Juan
Rich Man, Jessica
Armonaside, Daniel
Morales, Eduardo
Leon, Luis
Byrd, Sarah W.
Ugarde, Juan
Application Number:
JP2020520597A
Publication Date:
January 18, 2023
Filing Date:
October 09, 2018
Export Citation:
Assignee:
PSOMAGEN, INC.
International Classes:
C12Q1/6869
Other References:
Loose, M. et al.,Real-time selective sequencing using nanopore technology,Nat Methods.,2016年,13(9),751-754
Kivioja, T. et al.,Counting absolute numbers of molecules using unique molecular identifiers,Nature Methods,2011年,9(1),72-74
Hoshino, T. and Inagaki, F.,Application of stochastic labeling with random-sequence bacodes for simultaneous quantificaion and sequencing of environmental 16S rRNA genes,PLOS ONE,2017年01月04日,12(1),e0169431
Phipson, B. et al.,Gene length and detection bias in single cell RNA sequencing protocols,F1000Research,2017年04月28日,6:595
Kivioja, T. et al.,Counting absolute numbers of molecules using unique molecular identifiers,Nature Methods,2011年,9(1),72-74
Hoshino, T. and Inagaki, F.,Application of stochastic labeling with random-sequence bacodes for simultaneous quantificaion and sequencing of environmental 16S rRNA genes,PLOS ONE,2017年01月04日,12(1),e0169431
Phipson, B. et al.,Gene length and detection bias in single cell RNA sequencing protocols,F1000Research,2017年04月28日,6:595
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazuho
Kato Kazuho
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