Title:
睡眠誘発剤
Document Type and Number:
Japanese Patent JP4409767
Kind Code:
B2
Abstract:
A sleep-inducing preparation which comprises as an effective ingredient a prostaglandin derivative represented by the formula: wherein X is a halogen atom, Y is a group represented by (CH2)m, a cis-vinylene group or a phenylene group, Z is an ethylene group, a trans-vinylene group, OCH2 or S(O)nCH2, R<1> is a C3-10 cycloalkyl group, a C3-10 cycloalkyl group substituted with C1-4 alkyl group(s), a C4-13 cycloalkylalkyl group, a C5-10 alkyl group, a C5-10 alkenyl group, a C5-10 alkynyl group or a bridged cyclic hydrocarbon group, R<2> is a hydrogen atom, a C1-10 alkyl group or a C3-10 cycloalkyl group, m is an integer of 1 to 3, and n is 0, 1 or 2, a pharmaceutically acceptable salt thereof or a hydrate thereof.
Inventors:
Fumie Sato
Toru Tanami
Kazuya Kameo
Kenji Yamada
Okuyama Shigeru
Naoya Ono
Toru Tanami
Kazuya Kameo
Kenji Yamada
Okuyama Shigeru
Naoya Ono
Application Number:
JP2000550489A
Publication Date:
February 03, 2010
Filing Date:
May 25, 1999
Export Citation:
Assignee:
Taisho Pharmaceutical Co., Ltd.
Fumie Sato
Fumie Sato
International Classes:
A61K31/5575; A61K31/00; A61K31/557; A61P25/08; A61P25/20; C07C405/00
Domestic Patent References:
| JP7233144A | ||||
| JP7255929A |
Foreign References:
| WO1994002457A1 | ||||
| US0599838 |
Attorney, Agent or Firm:
Tomizo Kitagawa