PURPOSE: To provide a slow-releasing pharmaceutical composition having adhesivity and affinity to living body as well as shape-retainability, by compounding a methoxyethylene maleic anhydride copolymer, a cellulose deriva tive and a drug component.
CONSTITUTION: The objective slow-releasing pharmaceutical composition can be produced by compounding a drug component to a mixture of the methoxyethylene maleic anhydride copolymer of formula and a cellulose derivative (e.g. hydroxypropyl cellulose, chitin, chitosan, etc.). The ratio of the compound of formula to the cellulose derivative is preferably 70:30W30:70. Any drug component can be used for the purpose provided that the drug has to be administered frequently to keep the effective concentration in blood or in the diseased part. It is suitable as a drug preparation for peroral administration, oral cavity application, application to nasal cavity or administration into the tissue, and is used preferably in the form of powder, granule, tablet, etc. The rate of drug release in the living body can be controlled to enable the reduction of the administration frequency.
MATSUKI HIDEO
SUZUKI YOSHIKI
