Title:
小分子ブラジキニンB1受容体アンタゴニスト
Document Type and Number:
Japanese Patent JP2010539204
Kind Code:
A
Abstract:
Disclosed are compounds of formula (I) which are bradykinin B1 receptor (B1R) antagonists. These compounds are useful to treat diseases or relieve adverse symptoms associated with inflammation and pain. The invention encompasses novel compounds and acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases involving inflammation and pain.
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Inventors:
Lochal Day, Elsa
Danekel, Claus
Shout, Marco
Ushibe
Djärk
Fumer, Gerd
Reineke, Ulrich
Wolf, wolf
Danekel, Claus
Shout, Marco
Ushibe
Djärk
Fumer, Gerd
Reineke, Ulrich
Wolf, wolf
Application Number:
JP2010525265A
Publication Date:
December 16, 2010
Filing Date:
September 19, 2008
Export Citation:
Assignee:
The Elini Actien Gezershyaft
International Classes:
C07C237/38; A61K31/166; A61K31/40; A61K31/4025; A61K31/4155; A61K31/427; A61K31/433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/455; A61K31/4709; A61K31/496; A61K31/501; A61K31/502; A61K31/505; A61K31/506; A61K31/54; A61P1/04; A61P9/10; A61P19/06; A61P29/00; A61P37/02; A61P43/00; C07C281/06; C07D207/06; C07D207/20; C07D213/82; C07D213/89; C07D239/28; C07D239/42; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D413/12; C07D417/12; C07D495/04
Domestic Patent References:
| JP2005518374A | 2005-06-23 | |||
| JP2006513158A | 2006-04-20 | |||
| JP2006510609A | 2006-03-30 | |||
| JPH06502870A | 1994-03-31 | |||
| JP2007191461A | 2007-08-02 |
Foreign References:
| US5216165A | 1993-06-01 | |||
| US20050261327A1 | 2005-11-24 | |||
| US20070155739A1 | 2007-07-05 | |||
| WO2005035534A1 | 2005-04-21 | |||
| WO2005014576A1 | 2005-02-17 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office