Title:
強化剤を含む固体経口投与剤形
Document Type and Number:
Japanese Patent JP5450052
Kind Code:
B2
Abstract:
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal deliver of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form. The composition is administered to the patient before bedtime, within six hours after consuming food, medications or beverages other than water or daily, weekly or monthly at specific dosage regimens.
Inventors:
Leonardo, Thomas W.
Application Number:
JP2009504354A
Publication Date:
March 26, 2014
Filing Date:
April 09, 2007
Export Citation:
Assignee:
Merrion Research iii Limited
International Classes:
A61K31/663; A61K9/14; A61K9/20; A61K9/22; A61K9/24; A61K9/26; A61K9/28; A61K9/48; A61K9/52; A61K47/12; A61K47/14; A61K47/32; A61K47/38; A61P19/10; A61P29/00; A61P35/00
Domestic Patent References:
| JP2002541185A | ||||
| JP11510506A | ||||
| JP2002537321A |
Foreign References:
| US6468559 |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka