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Title:
SOLID PREPARATION CONTAINING LOXOPROFEN AND DIHYDROCODEINE PHOSPHATE
Document Type and Number:
Japanese Patent JP2018090549
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a solid preparation (particularly a tablet or a granule) containing loxoprofen or a salt thereof and dihydrocodeine phosphate, which is stable and prevents the content of active ingredients from decreasing.SOLUTION: A solid preparation contains (a) loxoprofen or a salt thereof, (b) dihydrocodeine phosphate, and (c) at least one silicic acid selected from the group consisting of hydrous silicon dioxide, light silicic anhydride, heavy silicic anhydride, silicon dioxide and particulate silicon dioxide.SELECTED DRAWING: None

Inventors:
MOCHIZUKI YUSUKE
INABA ETSUKO
KAMO TOMOARI
Application Number:
JP2016237225A
Publication Date:
June 14, 2018
Filing Date:
December 07, 2016
Export Citation:
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Assignee:
DAIICHI SANKYO HEALTHCARE CO LTD
International Classes:
A61K31/485; A61K9/16; A61K9/20; A61K31/136; A61K31/137; A61K31/192; A61K31/195; A61K31/198; A61K31/375; A61K31/40; A61K31/4402; A61K31/4741; A61K31/51; A61K31/52; A61K31/525; A61K31/7048; A61K47/02; A61P29/00
Domestic Patent References:
JP2014162743A2014-09-08
JP2011225528A2011-11-10
JP2016056166A2016-04-21
JP2012106973A2012-06-07
JP2012140420A2012-07-26
JP2014012661A2014-01-23
JP2006028171A2006-02-02
Other References:
第十六改正日本薬局方, vol. 2011年3月24日, JPN6020032511, pages 9 - 10, ISSN: 0004697858
第十五改正日本薬局方, vol. 2006年3月31日, JPN6020032513, pages 11 - 12, ISSN: 0004697859
Attorney, Agent or Firm:
Toshiyasu Takemoto
Kimiki Ishibashi