Title:
可溶性Ｃ５ａＲアンタゴニスト
Document Type and Number:
Japanese Patent JP7121722
Kind Code:
B2
Abstract:
Compounds are provided to modulate the C5a receptor. The compounds have the following Formula (I):including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Inventors:
Pinchen fan
Antoni Krasinski
Ben Kat Lady Mari
Sichang Miao
srinivas pana
Song Yang
Valentino Jay Stella
Zhong Epin
Pengry Jahn
Antoni Krasinski
Ben Kat Lady Mari
Sichang Miao
srinivas pana
Song Yang
Valentino Jay Stella
Zhong Epin
Pengry Jahn
Application Number:
JP2019502541A
Publication Date:
August 18, 2022
Filing Date:
April 03, 2017
Export Citation:
Assignee:
Chemocentrix, Incorporated
International Classes:
C07D211/60; A61K31/451; A61K31/661; A61K31/664; A61P1/00; A61P1/18; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/02; A61P13/12; A61P17/00; A61P17/02; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/08; A61P43/00; C07F9/09; C07F9/12; C07F9/24
Domestic Patent References:
| JP2013529647A | ||||
| JP2014510110A | ||||
| JP2009535295A | ||||
| JP2010502656A | ||||
| JP2015529681A | ||||
| JP2011522838A | ||||
| JP2001527083A | ||||
| JP2012513402A |
Foreign References:
| WO2014198647A2 | ||||
| WO2013032964A1 |
Other References:
STELLA V.J., Nti-Addae K.W.,Prodrug strategies to overcome poor water solubility,Advanced Drug Delivery Reviews,2007年,59,677-694
LARSEN, C. S. et al.,Textbook of Drug Design and Discovery,Charpter 14,2002年,p.460-514
BUNDGAARD H,NOVEL CHEMICAL APPROACHES IN PRODRUG DESIGN,DRUGS OF THE FUTURE,ES,PROUS SCIENCE,1991年05月01日,Vol.16, No.5,p.443-58
周東智,有機医薬分子論,2刷,2012年08月25日,p.169-171
製剤学・物理薬剤学,2版1刷,2012年,p.259-66
LARSEN, C. S. et al.,Textbook of Drug Design and Discovery,Charpter 14,2002年,p.460-514
BUNDGAARD H,NOVEL CHEMICAL APPROACHES IN PRODRUG DESIGN,DRUGS OF THE FUTURE,ES,PROUS SCIENCE,1991年05月01日,Vol.16, No.5,p.443-58
周東智,有機医薬分子論,2刷,2012年08月25日,p.169-171
製剤学・物理薬剤学,2版1刷,2012年,p.259-66
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Junichi Tsuruta
Tomohiro Nanzan
Youichi Watanabe
Naonori Koda
Shinji Mihashi
Junichi Tsuruta
Tomohiro Nanzan
Youichi Watanabe
Naonori Koda
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